Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46345
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
5543±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46345
Synonyms:
MLS000094160 | N-[(2-methyl-1,3-thiazol-4-yl)methyl]-4-phenoxy-benzenesulfonamide | N-[(2-methyl-1,3-thiazol-4-yl)methyl]-4-phenoxybenzenesulfonamide | N-[(2-methyl-4-thiazolyl)methyl]-4-phenoxybenzenesulfonamide | N-[(2-methylthiazol-4-yl)methyl]-4-phenoxy-benzenesulfonamide | SMR000016875 | cid_3244729
Type:
Small organic molecule
Emp. Form.:
C17H16N2O3S2
Mol. Mass.:
360.451
SMILES:
Cc1nc(CNS(=O)(=O)c2ccc(Oc3ccccc3)cc2)cs1
Structure:
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