Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52479
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
9325±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52479
Synonyms:
2-Hydroxy-benzoic acid N'-[1-(4-fluoro-benzyl)-2,4,6-trioxo-tetrahydro-pyrimidin-(5E)-ylidenemethyl]-hydrazide | MLS000588064 | N'-[(E)-[1-(4-fluorobenzyl)-2,4,6-triketo-hexahydropyrimidin-5-ylidene]methyl]-2-hydroxy-benzohydrazide | N'-[(E)-[1-[(4-fluorophenyl)methyl]-2,4,6-trioxo-1,3-diazinan-5-ylidene]methyl]-2-hydroxybenzohydrazide | N'-[(E)-[1-[(4-fluorophenyl)methyl]-2,4,6-tris(oxidanylidene)-1,3-diazinan-5-ylidene]methyl]-2-oxidanyl-benzohydrazide | SMR000220081 | cid_5518046
Type:
Small organic molecule
Emp. Form.:
C19H15FN4O5
Mol. Mass.:
398.3446
SMILES:
Oc1ccccc1C(=O)NNC=C1C(=O)NC(=O)N(Cc2ccc(F)cc2)C1=O |w:11.11|
Structure:
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