Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52767
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52767
Synonyms:
(2Z)-1-acetyl-2-(p-anisidinomethylene)pseudoindoxyl | (2Z)-1-acetyl-2-[(4-methoxyanilino)methylidene]-3-indolone | (2Z)-1-acetyl-2-[(4-methoxyanilino)methylidene]indol-3-one | (2Z)-1-ethanoyl-2-[[(4-methoxyphenyl)amino]methylidene]indol-3-one | 1-Acetyl-2-[1-(4-methoxy-phenylamino)-meth-(E)-ylidene]-1,2-dihydro-indol-3-one | MLS000778382 | SMR000415176 | cid_5414161
Type:
Small organic molecule
Emp. Form.:
C18H16N2O3
Mol. Mass.:
308.3312
SMILES:
COc1ccc(cc1)N=Cc1c(O)c2ccccc2n1C(C)=O |w:8.8|
Structure:
Search PDB for entries with ligand similarity: