Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52768
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
14034±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52768
Synonyms:
(5E)-4-(1,3-benzothiazol-2-yl)-5-(2-hydroxy-3-methyl-4-oxo-1-cyclohexa-2,5-dienylidene)-1,2-dihydropyrazole-3-carboxylic acid | (5E)-4-(1,3-benzothiazol-2-yl)-5-(2-hydroxy-3-methyl-4-oxocyclohexa-2,5-dien-1-ylidene)-1,2-dihydropyrazole-3-carboxylic acid | (5E)-4-(1,3-benzothiazol-2-yl)-5-(2-hydroxy-4-keto-3-methyl-cyclohexa-2,5-dien-1-ylidene)-3-pyrazoline-3-carboxylic acid | (5E)-4-(1,3-benzothiazol-2-yl)-5-(3-methyl-2-oxidanyl-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)-1,2-dihydropyrazole-3-carboxylic acid | 4-Benzothiazol-2-yl-5-(2,4-dihydroxy-3-methyl-phenyl)-2H-pyrazole-3-carboxylic acid | MLS000777941 | SMR000414335 | cid_16681760
Type:
Small organic molecule
Emp. Form.:
C18H13N3O4S
Mol. Mass.:
367.379
SMILES:
Cc1c(O)ccc(-c2n[nH]c(C(O)=O)c2-c2nc3ccccc3s2)c1O
Structure:
Search PDB for entries with ligand similarity: