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Target
Zinc finger protein mex-5
Ligand
BDBM52777
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
3831±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52777
Synonyms:
MLS000559965 | Methanesulfonic acid 3-oxo-2-[(E)-3-phenyl-prop-2-en-(Z)-ylidene]-2,3-dihydro-benzofuran-6-yl ester | SMR000439361 | [(2Z)-3-oxidanylidene-2-[(E)-3-phenylprop-2-enylidene]-1-benzofuran-6-yl] methanesulfonate | [(2Z)-3-oxo-2-[(E)-3-phenylprop-2-enylidene]-1-benzofuran-6-yl] methanesulfonate | cid_2015650 | methanesulfonic acid [(2Z)-3-keto-2-[(E)-3-phenylprop-2-enylidene]coumaran-6-yl] ester | methanesulfonic acid [(2Z)-3-oxo-2-[(E)-3-phenylprop-2-enylidene]-6-benzofuranyl] ester
Type:
Small organic molecule
Emp. Form.:
C18H14O5S
Mol. Mass.:
342.366
SMILES:
CS(=O)(=O)Oc1ccc2C(=O)\C(Oc2c1)=C\C=C\c1ccccc1
Structure:
Search PDB for entries with ligand similarity: