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Target
Zinc finger protein mex-5
Ligand
BDBM52778
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52778
Synonyms:
(2R)-2-amino-3-methyl-N-(5-quinoxalinylmethylideneamino)pentanamide;hydrochloride | (2R)-2-amino-3-methyl-N-(quinoxalin-5-ylmethyleneamino)valeramide;hydrochloride | (2R)-2-amino-3-methyl-N-(quinoxalin-5-ylmethylideneamino)pentanamide;hydrochloride | (2R)-2-azanyl-3-methyl-N-(quinoxalin-5-ylmethylideneamino)pentanamide;hydrochloride | (R)-2-Amino-3-methyl-pentanoic acid [1-quinoxalin-5-yl-meth-(E)-ylidene]-hydrazide | MLS000559956 | SMR000439352 | cid_16681817
Type:
Small organic molecule
Emp. Form.:
C15H19N5O
Mol. Mass.:
285.3443
SMILES:
CCC(C)[C@@H](N)C(=O)NN=Cc1cccc2nccnc12
Structure:
Search PDB for entries with ligand similarity: