Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52781
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
12670±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52781
Synonyms:
8-[2-(2,4-dioxopentan-3-ylidene)hydrazinyl]-1,3-dimethyl-7H-purine-2,6-dione | 8-[2-[2,4-bis(oxidanylidene)pentan-3-ylidene]hydrazinyl]-1,3-dimethyl-7H-purine-2,6-dione | 8-[N'-(1-Acetyl-2-oxo-propylidene)-hydrazino]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione | 8-[N'-(1-acetyl-2-keto-propylidene)hydrazino]-1,3-dimethyl-7H-purine-2,6-quinone | MLS001029871 | SMR000426812 | cid_915510
Type:
Small organic molecule
Emp. Form.:
C12H14N6O4
Mol. Mass.:
306.2774
SMILES:
CC(=O)C(=NNc1nc2n(C)c(=O)n(C)c(=O)c2[nH]1)C(C)=O |(15.6,-2.21,;14.06,-2.21,;13.29,-3.54,;13.29,-.87,;11.75,-.87,;10.98,.46,;9.44,.46,;8.54,-.78,;7.08,-.31,;5.75,-1.08,;5.75,-2.62,;4.41,-.31,;3.08,-1.08,;4.41,1.23,;3.08,2,;5.75,2,;5.75,3.54,;7.08,1.23,;8.54,1.7,;14.06,.46,;15.6,.46,;13.29,1.79,)|
Structure:
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