Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52783
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52783
Synonyms:
2-[(4E)-4-(1-anilinoethylidene)-1-(1,3-benzothiazol-2-yl)-5-keto-2-pyrazolin-3-yl]acetic acid methyl ester | 2-[(4E)-4-(1-anilinoethylidene)-1-(1,3-benzothiazol-2-yl)-5-oxo-3-pyrazolyl]acetic acid methyl ester | MLS000779088 | SMR000415776 | cid_7584226 | methyl 2-[(4E)-1-(1,3-benzothiazol-2-yl)-5-oxidanylidene-4-(1-phenylazanylethylidene)pyrazol-3-yl]ethanoate | methyl 2-[(4E)-4-(1-anilinoethylidene)-1-(1,3-benzothiazol-2-yl)-5-oxopyrazol-3-yl]acetate | {1-Benzothiazol-2-yl-5-oxo-4-[1-phenylamino-eth-(E)-ylidene]-4,5-dihydro-1H-pyrazol-3-yl}-acetic acid methyl ester
Type:
Small organic molecule
Emp. Form.:
C21H18N4O3S
Mol. Mass.:
406.458
SMILES:
COC(=O)Cc1[nH]n(-c2nc3ccccc3s2)c(=O)c1C(C)=Nc1ccccc1 |w:22.25|
Structure:
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