Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52784
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52784
Synonyms:
MLS000332836 | N-[3-cyano-1-(3-isopropoxypropyl)-5-keto-dipyrido[1,2-d:3',4'-f]pyrimidin-2-ylidene]thiophene-2-carboxamide | N-[3-cyano-5-oxidanylidene-1-(3-propan-2-yloxypropyl)dipyrido[1,2-d:3',4'-f]pyrimidin-2-ylidene]thiophene-2-carboxamide | N-[3-cyano-5-oxo-1-(3-propan-2-yloxypropyl)-2-dipyrido[1,2-d:3',4'-f]pyrimidinylidene]-2-thiophenecarboxamide | N-[3-cyano-5-oxo-1-(3-propan-2-yloxypropyl)dipyrido[1,2-d:3',4'-f]pyrimidin-2-ylidene]thiophene-2-carboxamide | SMR000436196 | Thiophene-2-carboxylic acid [3-cyano-1-(3-isopropoxy-propyl)-10-oxo-1,10-dihydro-1,9,10a-triaza-anthracen-(2E)-ylidene]-amide | cid_2028226
Type:
Small organic molecule
Emp. Form.:
C23H21N5O3S
Mol. Mass.:
447.51
SMILES:
CC(C)OCCCn1c2nc3ccccn3c(=O)c2cc(C#N)\c1=N/C(=O)c1cccs1
Structure:
Search PDB for entries with ligand similarity: