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Target
Zinc finger protein mex-5
Ligand
BDBM52786
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
228575±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52786
Synonyms:
MLS000332846 | N-[3-Cyano-1-(3-isopropoxy-propyl)-8-methyl-10-oxo-1,10-dihydro-1,9,10a-triaza-anthracen-(2E)-ylide ne]-acetamide | N-[3-cyano-1-(3-isopropoxypropyl)-5-keto-10-methyl-dipyrido[3,4-c:1',2'-f]pyrimidin-2-ylidene]acetamide | N-[3-cyano-10-methyl-5-oxidanylidene-1-(3-propan-2-yloxypropyl)dipyrido[3,4-c:1',2'-f]pyrimidin-2-ylidene]ethanamide | N-[3-cyano-10-methyl-5-oxo-1-(3-propan-2-yloxypropyl)-2-dipyrido[3,4-c:1',2'-f]pyrimidinylidene]acetamide | N-[3-cyano-10-methyl-5-oxo-1-(3-propan-2-yloxypropyl)dipyrido[3,4-c:1',2'-f]pyrimidin-2-ylidene]acetamide | SMR000436195 | cid_4331622
Type:
Small organic molecule
Emp. Form.:
C21H23N5O3
Mol. Mass.:
393.439
SMILES:
CC(C)OCCCn1c2nc3c(C)cccn3c(=O)c2cc(C#N)c1=NC(C)=O |w:25.28|
Structure:
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