Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52791
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52791
Synonyms:
4-[2,5-dimethyl-3-[[(6-methyl-4-oxo-1H-pyrimidin-2-yl)hydrazinylidene]methyl]-1-pyrrolyl]benzoic acid methyl ester | 4-[3-[[(4-keto-6-methyl-1H-pyrimidin-2-yl)hydrazono]methyl]-2,5-dimethyl-pyrrol-1-yl]benzoic acid methyl ester | MLS000773750 | SMR000364461 | cid_4396662 | methyl 4-[2,5-dimethyl-3-[[(6-methyl-4-oxidanylidene-1H-pyrimidin-2-yl)hydrazinylidene]methyl]pyrrol-1-yl]benzoate | methyl 4-[2,5-dimethyl-3-[[(6-methyl-4-oxo-1H-pyrimidin-2-yl)hydrazinylidene]methyl]pyrrol-1-yl]benzoate
Type:
Small organic molecule
Emp. Form.:
C20H21N5O3
Mol. Mass.:
379.4124
SMILES:
COC(=O)c1ccc(cc1)-n1c(C)cc(CN=Nc2nc(C)cc(=O)[nH]2)c1C |w:16.16|
Structure:
Search PDB for entries with ligand similarity: