Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52792
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
50155±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52792
Synonyms:
3-[2,5-dimethyl-3-[[(5-nitro-2-pyridinyl)hydrazinylidene]methyl]-1-pyrrolyl]-2-methylbenzoic acid | 3-[2,5-dimethyl-3-[[(5-nitro-2-pyridyl)hydrazono]methyl]pyrrol-1-yl]-2-methyl-benzoic acid | 3-[2,5-dimethyl-3-[[(5-nitropyridin-2-yl)hydrazinylidene]methyl]pyrrol-1-yl]-2-methyl-benzoic acid | 3-[2,5-dimethyl-3-[[(5-nitropyridin-2-yl)hydrazinylidene]methyl]pyrrol-1-yl]-2-methylbenzoic acid | 3-{2,5-Dimethyl-3-[(5-nitro-pyridin-2-yl)-hydrazonomethyl]-pyrrol-1-yl}-2-methyl-benzoic acid | MLS000776790 | SMR000413189 | cid_3479310
Type:
Small organic molecule
Emp. Form.:
C20H19N5O4
Mol. Mass.:
393.396
SMILES:
Cc1cc(CN=Nc2ccc(cn2)[N+]([O-])=O)c(C)n1-c1cccc(C(O)=O)c1C |w:5.4,(4.37,-2.82,;5.84,-2.35,;6.31,-.88,;7.85,-.88,;8.76,.36,;8.13,1.77,;9.04,3.02,;8.41,4.42,;9.31,5.67,;8.69,7.08,;7.16,7.24,;6.25,5.99,;6.88,4.58,;6.76,8.72,;7.85,9.81,;5.42,9.49,;8.33,-2.35,;9.79,-2.82,;7.08,-3.25,;7.08,-4.79,;8.41,-5.56,;8.41,-7.1,;7.08,-7.87,;5.75,-7.1,;4.41,-7.87,;4.41,-9.41,;3.08,-7.1,;5.75,-5.56,;4.41,-4.79,)|
Structure:
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