Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52794
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52794
Synonyms:
10-(3,4-Dimethoxy-phenyl)-3-furan-2-ylmethyl-4-imino-3,10-dihydro-4H-9-oxa-1,3-diaza-anthracen-7-ol | 4-azanylidene-5-(3,4-dimethoxyphenyl)-3-(furan-2-ylmethyl)-5H-chromeno[2,3-d]pyrimidin-8-ol | 5-(3,4-dimethoxyphenyl)-3-(2-furanylmethyl)-4-imino-5H-[1]benzopyrano[2,3-d]pyrimidin-8-ol | 5-(3,4-dimethoxyphenyl)-3-(2-furfuryl)-4-imino-5H-chromeno[2,3-d]pyrimidin-8-ol | 5-(3,4-dimethoxyphenyl)-3-(furan-2-ylmethyl)-4-imino-5H-chromeno[2,3-d]pyrimidin-8-ol | MLS000778759 | SMR000415536 | cid_5219557
Type:
Small organic molecule
Emp. Form.:
C24H21N3O5
Mol. Mass.:
431.4406
SMILES:
COc1ccc(cc1OC)C1c2ccc(O)cc2Oc2ncn(Cc3ccco3)c(=N)c12
Structure:
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