Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52797
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52797
Synonyms:
(2Z)-2-[1-(4-bromoanilino)ethylidene]-1-benzothiophen-3-one | (2Z)-2-[1-(4-bromoanilino)ethylidene]benzothiophen-3-one | (2Z)-2-[1-[(4-bromophenyl)amino]ethylidene]-1-benzothiophen-3-one | 2-[1-(4-Bromo-phenylamino)-eth-(Z)-ylidene]-benzo[b]thiophen-3-one | MLS000777104 | SMR000413500 | cid_5399975
Type:
Small organic molecule
Emp. Form.:
C16H12BrNOS
Mol. Mass.:
346.242
SMILES:
CC(=Nc1ccc(Br)cc1)c1sc2ccccc2c1O |w:2.2|
Structure:
Search PDB for entries with ligand similarity: