Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52799
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52799
Synonyms:
MLS000332913 | N-(4-{[1-[2-(3,4-Dimethoxy-phenyl)-ethyl]-2,4,6-trioxo-tetrahydro-pyrimidin-(5E)-ylidenemethyl]-amino}-p henyl)-acetamide | N-[4-[[(E)-(1-homoveratryl-2,4,6-triketo-hexahydropyrimidin-5-ylidene)methyl]amino]phenyl]acetamide | N-[4-[[(E)-[1-[2-(3,4-dimethoxyphenyl)ethyl]-2,4,6-trioxo-1,3-diazinan-5-ylidene]methyl]amino]phenyl]acetamide | N-[4-[[(E)-[1-[2-(3,4-dimethoxyphenyl)ethyl]-2,4,6-tris(oxidanylidene)-1,3-diazinan-5-ylidene]methyl]amino]phenyl]ethanamide | SMR000436229 | cid_5517961
Type:
Small organic molecule
Emp. Form.:
C23H24N4O6
Mol. Mass.:
452.4599
SMILES:
COc1ccc(CCN2C(=O)NC(=O)C(=CNc3ccc(NC(C)=O)cc3)C2=O)cc1OC |w:15.15|
Structure:
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