Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52803
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52803
Synonyms:
(5E)-5-(1H-indol-3-ylmethylene)-1-(tetrahydrofurfuryl)barbituric acid | (5E)-5-(1H-indol-3-ylmethylidene)-1-(2-oxolanylmethyl)-1,3-diazinane-2,4,6-trione | (5E)-5-(1H-indol-3-ylmethylidene)-1-(oxolan-2-ylmethyl)-1,3-diazinane-2,4,6-trione | 5-[1-(1H-Indol-3-yl)-meth-(E)-ylidene]-1-(tetrahydro-furan-2-ylmethyl)-pyrimidine-2,4,6-trione | MLS000768278 | SMR000431599 | cid_6246183
Type:
Small organic molecule
Emp. Form.:
C18H17N3O4
Mol. Mass.:
339.3453
SMILES:
O=C1NC(=O)\C(=C/c2c[nH]c3ccccc23)C(=O)N1CC1CCCO1
Structure:
Search PDB for entries with ligand similarity: