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Target
Zinc finger protein mex-5
Ligand
BDBM52804
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52804
Synonyms:
(5E)-5-[(5-methyl-2-thienyl)methylene]-1-(tetrahydrofurfuryl)barbituric acid | (5E)-5-[(5-methyl-2-thiophenyl)methylidene]-1-(2-oxolanylmethyl)-1,3-diazinane-2,4,6-trione | (5E)-5-[(5-methylthiophen-2-yl)methylidene]-1-(oxolan-2-ylmethyl)-1,3-diazinane-2,4,6-trione | 5-[1-(5-Methyl-thiophen-2-yl)-meth-(E)-ylidene]-1-(tetrahydro-furan-2-ylmethyl)-pyrimidine-2,4,6-trione | MLS000768277 | SMR000431598 | cid_5920838
Type:
Small organic molecule
Emp. Form.:
C15H16N2O4S
Mol. Mass.:
320.364
SMILES:
Cc1ccc(\C=C2/C(=O)NC(=O)N(CC3CCCO3)C2=O)s1
Structure:
Search PDB for entries with ligand similarity: