Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52806
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52806
Synonyms:
(5Z)-1-(3,5-dimethylphenyl)-5-[[5-(4-methyl-1-piperazinyl)-2-furanyl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione | (5Z)-1-(3,5-dimethylphenyl)-5-[[5-(4-methylpiperazin-1-yl)furan-2-yl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione | (5Z)-1-(3,5-dimethylphenyl)-5-[[5-(4-methylpiperazino)-2-furyl]methylene]-2-thioxo-hexahydropyrimidine-4,6-quinone | 1-(3,5-Dimethyl-phenyl)-5-[1-[5-(4-methyl-piperazin-1-yl)-furan-2-yl]-meth-(Z)-ylidene]-2-thioxo-dihydro-p yrimidine-4,6-dione | MLS000332853 | SMR000436123 | cid_1552653
Type:
Small organic molecule
Emp. Form.:
C22H24N4O3S
Mol. Mass.:
424.516
SMILES:
CN1CCN(CC1)c1ccc(C=C2C(=O)NC(=S)N(C2=O)c2cc(C)cc(C)c2)o1 |w:11.11|
Structure:
Search PDB for entries with ligand similarity: