Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52808
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52808
Synonyms:
1-(2-Diethylamino-ethyl)-5-(4-fluoro-phenyl)-3-hydroxy-4-(7-methoxy-benzofuran-2-carbonyl)-1,5-dihydr o-pyrrol-2-one | 1-[2-(diethylamino)ethyl]-2-(4-fluorophenyl)-3-[(7-methoxy-1-benzofuran-2-yl)carbonyl]-4-oxidanyl-2H-pyrrol-5-one | 1-[2-(diethylamino)ethyl]-2-(4-fluorophenyl)-4-hydroxy-3-(7-methoxy-1-benzofuran-2-carbonyl)-2H-pyrrol-5-one | 1-[2-(diethylamino)ethyl]-2-(4-fluorophenyl)-4-hydroxy-3-[(7-methoxy-2-benzofuranyl)-oxomethyl]-2H-pyrrol-5-one | 1-[2-(diethylamino)ethyl]-5-(4-fluorophenyl)-3-hydroxy-4-(7-methoxybenzofuran-2-carbonyl)-3-pyrrolin-2-one | MLS000332950 | SMR000436307 | cid_4370788
Type:
Small organic molecule
Emp. Form.:
C26H27FN2O5
Mol. Mass.:
466.5014
SMILES:
CCN(CC)CCN1C(C(C(=O)c2cc3cccc(OC)c3o2)C(=O)C1=O)c1ccc(F)cc1
Structure:
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