Reaction Details Report a problem with these data
Target
Neutrophil cytosol factor 1 [S99G]
Ligand
BDBM55794
Substrate
n/a
Meas. Tech.
Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs)
IC50
1310±n/a nM
Citation
 PubChem, PC Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) PubChem Bioassay (2008)[AID] 
Target
Name:
Neutrophil cytosol factor 1 [S99G]
Synonyms:
NCF1 | NCF1_HUMAN | NOXO2 | SH3PXD1A | neutrophil cytosolic factor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44664.39
Organism:
Homo sapiens (Human)
Description:
gi_115298672
Residue:
390
Sequence:
MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLILNRCSESTKRKLASAV
  
Inhibitor
Name:
BDBM55794
Synonyms:
1-amino-9,10-diketo-anthracene-2-carboxylic acid | 1-amino-9,10-dioxo-2-anthracenecarboxylic acid | 1-amino-9,10-dioxoanthracene-2-carboxylic acid | 1-azanyl-9,10-bis(oxidanylidene)anthracene-2-carboxylic acid | MLS000713412 | SMR000272893 | cid_6701
Type:
Small organic molecule
Emp. Form.:
C15H9NO4
Mol. Mass.:
267.2363
SMILES:
Nc1c(ccc2C(=O)c3ccccc3C(=O)c12)C(O)=O
Structure:
Search PDB for entries with ligand similarity: