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Target
Sentrin-specific protease 8
Ligand
BDBM76413
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM76413
Synonyms:
4-[(3-chloro-4-fluoro-phenyl)carbamoylamino]benzoic acid methyl ester | 4-[[(3-chloro-4-fluoroanilino)-oxomethyl]amino]benzoic acid methyl ester | MLS000537803 | SMR000144041 | cid_978194 | methyl 4-({[(3-chloro-4-fluorophenyl)amino]carbonyl}amino)benzoate | methyl 4-[(3-chloranyl-4-fluoranyl-phenyl)carbamoylamino]benzoate | methyl 4-[(3-chloro-4-fluorophenyl)carbamoylamino]benzoate
Type:
Small organic molecule
Emp. Form.:
C15H12ClFN2O3
Mol. Mass.:
322.719
SMILES:
COC(=O)c1ccc(NC(=O)Nc2ccc(F)c(Cl)c2)cc1
Structure:
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