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Target
Caspase-3
Ligand
BDBM77504
Substrate
n/a
Meas. Tech.
Absorbance-based biochemical high throughput dose response assay for activators of procaspase-3
EC50
>85267±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay for activators of procaspase-3 PubChem Bioassay (2010)[AID] 
Target
Name:
Caspase-3
Synonyms:
Apopain | CASP-3 | CASP3 | CASP3_HUMAN | CPP-32 | CPP32 | Caspase 3 | Caspase-3 subunit p12 | Caspase-3 subunit p17 | Cysteine protease CPP32 | SCA-1 | SREBP cleavage activity 1 | Yama protein | caspase-3 preproprotein
Type:
Hydrolase; heterotetramer of two heterodimers
Mol. Mass.:
31607.55
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
277
Sequence:
MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
  
Inhibitor
Name:
BDBM77504
Synonyms:
1,3,5-triphenyl-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6(1H,5H)-dione | 1,3,5-triphenyl-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione | 1,3,5-triphenyl-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-quinone | MLS000681118 | SMR000269383 | cid_2900872
Type:
Small organic molecule
Emp. Form.:
C23H17N3O2
Mol. Mass.:
367.4
SMILES:
Oc1n(-c2ccccc2)c(=O)c2c([nH]n(-c3ccccc3)c12)-c1ccccc1
Structure:
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