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Target
Dipeptidyl peptidase 1
Ligand
BDBM81399
Substrate
n/a
Meas. Tech.
Fluorogenic Assay
IC50
700±0.0 nM
Citation
 Deu, E; Leyva, MJ; Albrow, VE; Rice, MJ; Ellman, JA; Bogyo, M Functional studies of Plasmodium falciparum dipeptidyl aminopeptidase I using small molecule inhibitors and active site probes. Chem Biol 17:808-19 (2010) [PubMed]  Article 
Target
Name:
Dipeptidyl peptidase 1
Synonyms:
CATC_MOUSE | Ctsc | Dipeptidyl peptidase I
Type:
PROTEIN
Mol. Mass.:
52379.83
Organism:
Mus musculus
Description:
ChEMBL_44964
Residue:
462
Sequence:
MGPWTHSLRAVLLLVLLGVCTVRSDTPANCTYPDLLGTWVFQVGPRSSRSDINCSVMEATEEKVVVHLKKLDTAYDELGNSGHFTLIYNQGFEIVLNDYKWFAFFKYEVRGHTAISYCHETMTGWVHDVLGRNWACFVGKKVESHIEKVNMNAAHLGGLQERYSERLYTHNHNFVKAINTVQKSWTATAYKEYEKMSLRDLIRRSGHSQRIPRPKPAPMTDEIQQQILNLPESWDWRNVQGVNYVSPVRNQESCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEESCFPYTAKDSPCKPRENCLRYYSSDYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGRDPVTGIEYWIIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAIPIPKL
  
Inhibitor
Name:
BDBM81399
Synonyms:
ML4046A
Type:
Small organic molecule
Emp. Form.:
C23H30F4N4O2
Mol. Mass.:
470.5035
SMILES:
CCCCC(C(=O)COc1c(F)c(F)cc(F)c1F)n1cc(nn1)[C@@](C)(N)C1CCCCC1 |r,w:4.3|
Structure:
Search PDB for entries with ligand similarity: