Reaction Details Report a problem with these data
Target
Carbonic anhydrase 7
Ligand
BDBM50025093
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7.4±0
Temperature
298.15±0 K
Ki
53±0.0 nM
Citation
 Carta, F; Pothen, B; Maresca, A; Tiwari, M; Singh, V; Supuran, CT Carbonic anhydrase inhibitors: inhibition of cytosolic carbonic anhydrase isozymes II and VII with simple aromatic sulfonamides and some azo dyes. Chem Biol Drug Des 74:196-202 (2009) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50025093
Synonyms:
4-Chloro-benzenesulfonamide | CHEMBL804 | P-Chlorobenzenesulfonamide | p-Halide-sulfanilamide derivative, 2
Type:
Small organic molecule
Emp. Form.:
C6H6ClNO2S
Mol. Mass.:
191.635
SMILES:
NS(=O)(=O)c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: