Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM82016
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2820
Citation
 Schwabe, U; Ukena, D; Lohse, MJ Xanthine derivatives as antagonists at A1 and A2 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol 330:212-21 (1985) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM82016
Synonyms:
CAS_479-18-5 | DYPHYLLINE | Dihydroxypropyltheophylline | Diprophylline | Dylin | Dylix | Lufyllin | NSC_3182 | Neothylline
Type:
Small organic molecule
Emp. Form.:
C10H14N4O4
Mol. Mass.:
254.2426
SMILES:
Cn1c2ncn(CC(O)CO)c2c(=O)n(C)c1=O
Structure:
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