Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM82016
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2820
Citation
 Schwabe, U; Ukena, D; Lohse, MJ Xanthine derivatives as antagonists at A1 and A2 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol 330:212-21 (1985) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM82016
Synonyms:
CAS_479-18-5 | DYPHYLLINE | Dihydroxypropyltheophylline | Diprophylline | Dylin | Dylix | Lufyllin | NSC_3182 | Neothylline
Type:
Small organic molecule
Emp. Form.:
C10H14N4O4
Mol. Mass.:
254.2426
SMILES:
Cn1c2ncn(CC(O)CO)c2c(=O)n(C)c1=O
Structure:
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