Reaction Details Report a problem with these data
Target
Endoribonuclease toxin MazF
Ligand
BDBM83476
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen
EC50
>99000±n/a nM
Citation
 PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM83476
Synonyms:
(2-oxidanylidene-1H-quinolin-3-yl)methyl 3-methylbenzoate | (2-oxo-1H-quinolin-3-yl)methyl 3-methylbenzoate | 3-methylbenzoic acid (2-keto-1H-quinolin-3-yl)methyl ester | 3-methylbenzoic acid (2-oxo-1H-quinolin-3-yl)methyl ester | MLS000081238 | SMR000059805 | cid_663555
Type:
Small organic molecule
Emp. Form.:
C18H15NO3
Mol. Mass.:
293.3166
SMILES:
Cc1cccc(c1)C(=O)OCc1cc2ccccc2[nH]c1=O
Structure:
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