Reaction Details Report a problem with these data
Target
Endoribonuclease toxin MazF
Ligand
BDBM67581
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen
EC50
>99000±n/a nM
Citation
 PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM67581
Synonyms:
MLS000050452 | N-(5-chloranyl-2-oxidanyl-phenyl)-2-ethoxy-benzamide | N-(5-chloro-2-hydroxy-phenyl)-2-ethoxy-benzamide | N-(5-chloro-2-hydroxyphenyl)-2-ethoxybenzamide | SMR000076353 | cid_2953683
Type:
Small organic molecule
Emp. Form.:
C15H14ClNO3
Mol. Mass.:
291.73
SMILES:
CCOc1ccccc1C(=O)Nc1cc(Cl)ccc1O
Structure:
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