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Target
Cannabinoid receptor 2
Ligand
BDBM50255235
Substrate
n/a
Meas. Tech.
ChEBML_1686990
IC50
>10000±n/a nM
Citation
 Aghazadeh Tabrizi, M; Baraldi, PG; Baraldi, S; Ruggiero, E; De Stefano, L; Rizzolio, F; Di Cesare Mannelli, L; Ghelardini, C; Chicca, A; Lapillo, M; Gertsch, J; Manera, C; Macchia, M; Martinelli, A; Granchi, C; Minutolo, F; Tuccinardi, T Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors. J Med Chem 61:1340-1354 (2018) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50255235
Synonyms:
CHEMBL4078924
Type:
Small organic molecule
Emp. Form.:
C30H31N3O2
Mol. Mass.:
465.586
SMILES:
Cc1cccc(Cn2nc(cc2-c2ccc(O)cc2)C(=O)N2CCC(Cc3ccccc3)CC2)c1
Structure:
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