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Target
Free fatty acid receptor 1
Ligand
BDBM50265879
Substrate
n/a
Meas. Tech.
ChEMBL_1700322 (CHEMBL4051304)
EC50
1300±n/a nM
Citation
 McCoull, W; Bailey, A; Barton, P; Birch, AM; Brown, AJ; Butler, HS; Boyd, S; Butlin, RJ; Chappell, B; Clarkson, P; Collins, S; Davies, RM; Ertan, A; Hammond, CD; Holmes, JL; Lenaghan, C; Midha, A; Morentin-Gutierrez, P; Moore, JE; Raubo, P; Robb, G Indazole-6-phenylcyclopropylcarboxylic Acids as Selective GPR120 Agonists with in Vivo Efficacy. J Med Chem 60:3187-3197 (2017) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1_MOUSE | Ffar1 | Gpr40
Type:
PROTEIN
Mol. Mass.:
31818.80
Organism:
Mus musculus
Description:
ChEMBL_1454431
Residue:
300
Sequence:
MDLPPQLSFALYVSAFALGFPLNLLAIRGAVSHAKLRLTPSLVYTLHLGCSDLLLAITLPLKAVEALASGAWPLPLPFCPVFALAHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAIRRPRYSWGVCVAIWALVLCHLGLALGLETSGSWLDNSTSSLGINIPVNGSPVCLEAWDPDSARPARLSFSILLFFLPLVITAFCYVGCLRALVRSGLSHKRKLRAAWVAGGALLTLLLCLGPYNASNVASFINPDLGGSWRKLGLITGAWSVVLNPLVTGYLGTGPGRGTICVTRTQRGTIQK
  
Inhibitor
Name:
BDBM50265879
Synonyms:
CHEMBL4065429
Type:
Small organic molecule
Emp. Form.:
C28H23N3O3
Mol. Mass.:
449.5005
SMILES:
OC(=O)CCc1ccc(cc1)-c1ccc2c(OCc3ccccc3)nn(-c3ccccn3)c2c1
Structure:
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