Reaction Details Report a problem with these data
Target
Alpha-xylosidase
Ligand
BDBM50270473
Substrate
n/a
Meas. Tech.
ChEBML_1709226
IC50
400000±n/a nM
Citation
 Flores-Bocanegra, L; González-Andrade, M; Bye, R; Linares, E; Mata, R ?-Glucosidase Inhibitors from Salvia circinata. J Nat Prod 80:1584-1593 (2017) [PubMed]  Article 
Target
Name:
Alpha-xylosidase
Synonyms:
3.2.1.177 | Alpha-glucosidase | Alpha-xylosidase | ERS852394_00763 | yicI
Type:
PROTEIN
Mol. Mass.:
77058.74
Organism:
Blautia obeum
Description:
ChEMBL_117769
Residue:
663
Sequence:
MIRKYRYGAPFDTEALTEKIETAEEAFPYGEISQKEGFAFTYIMDEDDIVYGLGESNRGINKRGYCYISNCTDDPIHTEDKRSLYGAHNFIIVSGKTTFGLFFDYPSKLTFDIGYTRMDTLKVSCENADLDIYVIEGENAYDIVKQFRRVIGRSYIPPKFAFGFGQSRWGYTTKEDFRAVAKGYRENHIPIDMIYMDIDYMQDFKDFTVNEKNFPDFPEFVKEMKDQELRLIPIIDAGVKVEKGYEVYEEGVKNNYFCKREDGSDFVAAVWPGDTHFPDMLNPEARKWFGDKYRFLIDQGIEGFWNDMNEPAIFYSSEGLAEAKEFAGEFAKDTEGKIHPWAMQAKMKDIVNSPEDYKRFYHNVNGKKIRHDKVHNLFGYNMTRAAGEAFERIDPEKRFLMFSRSSYIGMHRYGGIWMGDNKSWWSHILLNLKMLPSLNMCGFMYTGADLGGFGDDTTRDLLLRFLALGVFTPLMRDHAAEGTREQECYQFENIEDFRSVINARYRLVPYLYSEYMKAALNDDMYFKPLGFVYPDDKMAIRVEDQLMLGNEIMIAPVYEQNARGRYVYLPEEMKFIKFMPDGSISEEVLEKGVHYVDVALNEVPLFIRSGKCIPVAEAAECVKDIDTENMQLIGYEGSSYTLYEDDGIHKDYDKKENYRVLTK
  
Inhibitor
Name:
BDBM50270473
Synonyms:
CHEMBL4127208
Type:
Small organic molecule
Emp. Form.:
C26H36O9
Mol. Mass.:
492.5586
SMILES:
[H][C@@]1(C[C@@]2([H])[C@@]3(COC(=O)C3=C1)CC[C@@H](C)[C@@]2(C)CCc1ccoc1)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r,c:11|
Structure:
Search PDB for entries with ligand similarity: