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Target
Oxytocin receptor
Ligand
BDBM50013631
Substrate
n/a
Meas. Tech.
ChEMBL_149182 (CHEMBL762745)
Ki
49±n/a nM
Citation
 Freidinger, RM; Williams, PD; Tung, RD; Bock, MG; Pettibone, DJ; Clineschmidt, BV; DiPardo, RM; Erb, JM; Garsky, VM; Gould, NP Cyclic hexapeptide oxytocin antagonists. Potency-, selectivity-, and solubility-enhancing modifications. J Med Chem 33:1843-5 (1990) [PubMed]  Article 
Target
Name:
Oxytocin receptor
Synonyms:
OT-R | OXYR_RAT | Otr | Oxtr | Oxytocin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42889.28
Organism:
RAT
Description:
Oxytocin OXTR RAT::P70536
Residue:
388
Sequence:
MEGTPAANWSVELDLGSGVPPGEEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLGTWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAAEGNDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDVNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFFCCSARYLKGSRPGETSVSKKSNSSTFVLSRRSSSQRSCSQPSSA
  
Inhibitor
Name:
BDBM50013631
Synonyms:
24-benzyl-16-(4-ethoxybenzyl)-25-methyl-13-[1-methyl-(1S)-propyl]perhydrodipyrido[1,2-a:1,2-d]pyrrolo[1,2-j][1,4,7,10,13,16]hexaazacyclooctadecine-6,12,15,18,23,26-hexaone | CHEMBL2372926
Type:
Small organic molecule
Emp. Form.:
C44H60N6O7
Mol. Mass.:
784.9832
SMILES:
[H][C@@]12CCCN1C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@]1([H])CCCCN1C(=O)[C@@]1([H])CCCCN1C(=O)[C@@]([H])(NC(=O)[C@@H](Cc1ccc(OCC)cc1)NC2=O)[C@@H](C)CC
Structure:
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