Reaction Details Report a problem with these data
Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50015516
Substrate
n/a
Meas. Tech.
ChEBML_52357
Ki
50±n/a nM
Citation
 Matassa, VG; Maduskuie, TP; Shapiro, HS; Hesp, B; Snyder, DW; Aharony, D; Krell, RD; Keith, RA Evolution of a series of peptidoleukotriene antagonists: synthesis and structure/activity relationships of 1,3,5-substituted indoles and indazoles. J Med Chem 33:1781-90 (1990) [PubMed]  Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
GUINEA PIG
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50015516
Synonyms:
4-[6-(2-Cyclopentyl-acetylamino)-indazol-1-ylmethyl]-3-methoxy-benzoic acid | CHEMBL49519
Type:
Small organic molecule
Emp. Form.:
C23H25N3O4
Mol. Mass.:
407.4623
SMILES:
COc1cc(ccc1Cn1ncc2ccc(NC(=O)CC3CCCC3)cc12)C(O)=O
Structure:
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