Reaction Details Report a problem with these data
Target
Chromobox protein homolog 7
Ligand
BDBM50189780
Substrate
n/a
Meas. Tech.
ChEMBL_1723537 (CHEMBL4138815)
Kd
29000±n/a nM
Citation
 Teske, KA; Hadden, MK Methyllysine binding domains: Structural insight and small molecule probe development. Eur J Med Chem 136:14-35 (2017) [PubMed]  Article 
Target
Name:
Chromobox protein homolog 7
Synonyms:
CBX7 | CBX7_HUMAN | Chromobox protein homolog 7 | Chromobox protein homolog 7 (CBX7)
Type:
Protein
Mol. Mass.:
28351.76
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
251
Sequence:
MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVKAGAPELVDKGPLVPTLPFPLRKPRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPPAPDVLQAAGEWEPAAQPPEEEADADLAEGPPPWTPALPSSEVTVTDITANSITVTFREAQAAEGFFRDRSGKF
  
Inhibitor
Name:
BDBM50189780
Synonyms:
CHEMBL3827954
Type:
Small organic molecule
Emp. Form.:
C22H26N2O5
Mol. Mass.:
398.4522
SMILES:
COc1cccc(C(=O)N2CCN(CC2)C(=O)COc2cccc(C)c2)c1OC
Structure:
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