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Target
Delta-type opioid receptor
Ligand
BDBM50018640
Substrate
n/a
Meas. Tech.
ChEBML_129933
IC50
740±n/a nM
Citation
 Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Structure-activity relationships of cyclic opioid peptide analogues containing a phenylalanine residue in the 3-position. J Med Chem 30:2094-9 (1987) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50018640
Synonyms:
10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid amide | CHEMBL302408
Type:
Small organic molecule
Emp. Form.:
C24H29N5O5S2
Mol. Mass.:
531.648
SMILES:
N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O
Structure:
Search PDB for entries with ligand similarity: