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Target
Monoglyceride lipase
Ligand
BDBM66023
Substrate
n/a
Meas. Tech.
ChEMBL_1743305 (CHEMBL4177815)
IC50
88±n/a nM
Citation
 Tuo, W; Leleu-Chavain, N; Spencer, J; Sansook, S; Millet, R; Chavatte, P Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors. J Med Chem 60:4-46 (2017) [PubMed]  Article 
Target
Name:
Monoglyceride lipase
Synonyms:
MAGL | MGLL_RAT | Mgl2 | Mgll | Monoacylglycerol lipase | Monoglyceride lipase | Monoglyceride lipase (MGL)
Type:
Enzyme
Mol. Mass.:
33505.38
Organism:
Rattus norvegicus (Rat)
Description:
Q8R431
Residue:
303
Sequence:
MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDELAQMLKRLDMLVFAHDHVGHGQSEGERMVVSDFQVFVRDLLQHVNTVQKDYPEVPVFLLGHSMGGAISILAAAERPTHFSGMILISPLILANPESASTLKVLAAKLLNFVLPNISLGRIDSSVLSRNKSEVDLYNSDPLICHAGVKVCFGIQLLNAVSRVERAMPRLTLPFLLLQGSADRLCDSKGAYLLMESSPSQDKTLKMYEGAYHVLHKELPEVTNSVLHEINTWVSHRIAVAGARCLP
  
Inhibitor
Name:
BDBM66023
Synonyms:
2-octyl-1,2-thiazol-3-one | 2-octyl-3-isothiazolone | 2-octyl-4-isothiazolin-3-one | MLS002415697 | SMR001370885 | cid_33528
Type:
Small organic molecule
Emp. Form.:
C11H19NOS
Mol. Mass.:
213.34
SMILES:
CCCCCCCCn1sccc1=O
Structure:
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