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Target
Adenosine kinase
Ligand
BDBM50456504
Substrate
n/a
Meas. Tech.
ChEMBL_1757324 (CHEMBL4192332)
Ki
>50000±n/a nM
Citation
 Brogi, S; Ramunno, A; Savi, L; Chemi, G; Alfano, G; Pecorelli, A; Pambianchi, E; Galatello, P; Compagnoni, G; Focher, F; Biamonti, G; Valacchi, G; Butini, S; Gemma, S; Campiani, G; Brindisi, M First dual AK/GSK-3? inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents. Eur J Med Chem 138:438-457 (2017) [PubMed]  Article 
Target
Name:
Adenosine kinase
Synonyms:
ADK | ADK_HUMAN
Type:
PROTEIN
Mol. Mass.:
40545.97
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1467841
Residue:
362
Sequence:
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH
  
Inhibitor
Name:
BDBM50456504
Synonyms:
CHEMBL4214720
Type:
Small organic molecule
Emp. Form.:
C22H15NOS
Mol. Mass.:
341.426
SMILES:
O=C1C(Sc2ccccc2-n2cccc12)c1cccc2ccccc12
Structure:
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