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Target
Glutathione S-transferase omega-1
Ligand
BDBM50458520
Substrate
n/a
Meas. Tech.
ChEMBL_1764008 (CHEMBL4199255)
IC50
54±n/a nM
Citation
 Xie, Y; Dahlin, JL; Oakley, AJ; Casarotto, MG; Board, PG; Baell, JB Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example. J Med Chem 61:7448-7470 (2018) [PubMed]  Article 
Target
Name:
Glutathione S-transferase omega-1
Synonyms:
GSTO 1-1 | GSTO1 | GSTO1_HUMAN | GSTTLP28 | Glutathione S-transferase omega-1 | Glutathione transferase omega 1 | glutathione S-transferase omega-1 isoform 1
Type:
PROTEIN
Mol. Mass.:
27565.54
Organism:
Homo sapiens (Human)
Description:
EBI_11172
Residue:
241
Sequence:
MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL
  
Inhibitor
Name:
BDBM50458520
Synonyms:
CHEMBL1486332
Type:
Small organic molecule
Emp. Form.:
C21H23ClFN3O2
Mol. Mass.:
403.878
SMILES:
Fc1ccc(cc1)N(C(C(=O)NC1CCCCC1)c1cccnc1)C(=O)CCl
Structure:
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