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Target
Carbonic anhydrase 2
Ligand
BDBM50454088
Substrate
n/a
Meas. Tech.
ChEMBL_1775581 (CHEMBL4232573)
Ki
3410±n/a nM
Citation
 Mujumdar, P; Bua, S; Supuran, CT; Peat, TS; Poulsen, SA Synthesis, structure and bioactivity of primary sulfamate-containing natural products. Bioorg Med Chem Lett 28:3009-3013 (2018) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50454088
Synonyms:
5''-O-(Sulfamoyl)Adenosine | 5''-O-Sulfamoyladenosine | CHEMBL471144
Type:
Small organic molecule
Emp. Form.:
C10H14N6O6S
Mol. Mass.:
346.32
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]1O |r|
Structure:
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