BDBM50454088 5''-O-(Sulfamoyl)Adenosine::5''-O-Sulfamoyladenosine::CHEMBL471144

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]1O

InChI Key InChIKey=GNZLUJQJDPRUTD-KQYNXXCUSA-N

Data  7 KI

PDB links: 8 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50454088   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50454088(5''-O-(Sulfamoyl)Adenosine | 5''-O-Sulfamoyladenos...)
Affinity DataKi:  1.03E+3nMAssay Description:Binding affinity to adenosine A1 receptor in rat brain membranes by measuring displacement of specific [3H]PIA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50454088(5''-O-(Sulfamoyl)Adenosine | 5''-O-Sulfamoyladenos...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of recombinant human CA9 expressed in Escherichia coli assessed as reduction in CO2 hydration by stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50454088(5''-O-(Sulfamoyl)Adenosine | 5''-O-Sulfamoyladenos...)
Affinity DataKi:  3.41E+3nMAssay Description:Inhibition of recombinant human CA2 expressed in Escherichia coli assessed as reduction in CO2 hydration by stopped flow assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50454088(5''-O-(Sulfamoyl)Adenosine | 5''-O-Sulfamoyladenos...)
Affinity DataKi:  4.45E+3nMAssay Description:Inhibition of recombinant human CA4 expressed in Escherichia coli assessed as reduction in CO2 hydration by stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50454088(5''-O-(Sulfamoyl)Adenosine | 5''-O-Sulfamoyladenos...)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity to adenosine A2A receptor in rat striatal membranes by measuring displacement of specific [3H]-CGS- 21680 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50454088(5''-O-(Sulfamoyl)Adenosine | 5''-O-Sulfamoyladenos...)
Affinity DataKi:  6.35E+3nMAssay Description:Inhibition of recombinant human CA1 expressed in Escherichia coli assessed as reduction in CO2 hydration by stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Rattus norvegicus)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50454088(5''-O-(Sulfamoyl)Adenosine | 5''-O-Sulfamoyladenos...)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity determined by displacement of specific binding of [125I]N-(4-amino-3-iodophenethyl)-adenosine in membranes of CHO cells stably trans...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed