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Target
P2Y purinoceptor 11
Ligand
BDBM50477240
Substrate
n/a
Meas. Tech.
ChEMBL_451010 (CHEMBL900091)
EC50
479±n/a nM
Citation
 Greve, H; Meis, S; Kassack, MU; Kehraus, S; Krick, A; Wright, AD; König, GM New iantherans from the marine sponge Ianthella quadrangulata: novel agonists of the P2Y(11) receptor. J Med Chem 50:5600-7 (2007) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 11
Synonyms:
P2RY11 | P2Y purinoceptor 11 | P2Y11 | P2Y11_HUMAN | Purinergic receptor P2Y11
Type:
PROTEIN
Mol. Mass.:
40366.02
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1362532
Residue:
374
Sequence:
MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNCSVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTVAEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATAAPKPSEPQSRELSQ
  
Inhibitor
Name:
BDBM50477240
Synonyms:
8-CARBOXY-ISO-IANTHERAN A
Type:
Small organic molecule
Emp. Form.:
C33H16Br4Na2O14S2
Mol. Mass.:
1066.197
SMILES:
[Na;v0+].[Na;v0+].[#8]-[#6](=O)-c1c(oc2c(Br)cc(\[#6]=[#6](/[#8]S([#8-])(=O)=O)\[#6](\[#8]S([#8-])(=O)=O)=[#6]\c3cc(Br)c4oc(cc4c3)-c3ccc(-[#8])c(Br)c3)cc12)-c1ccc(-[#8])c(Br)c1
Structure:
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