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Target
Luciferin 4-monooxygenase
Ligand
BDBM39025
Substrate
n/a
Meas. Tech.
ChEMBL_476208 (CHEMBL923739)
IC50
100±n/a nM
Citation
 Auld, DS; Southall, NT; Jadhav, A; Johnson, RL; Diller, DJ; Simeonov, A; Austin, CP; Inglese, J Characterization of chemical libraries for luciferase inhibitory activity. J Med Chem 51:2372-86 (2008) [PubMed]  Article 
Target
Name:
Luciferin 4-monooxygenase
Synonyms:
LUCI_PHOPY | Luciferase
Type:
PROTEIN
Mol. Mass.:
60747.46
Organism:
Photinus pyralis
Description:
ChEMBL_938513
Residue:
550
Sequence:
MEDAKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSGSTGLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVVPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGELPAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILIKAKKGGKSKL
  
Inhibitor
Name:
BDBM39025
Synonyms:
2-[5-(2-naphthyl)-1,2,4-oxadiazol-3-yl]pyridine | 5-(2-naphthalenyl)-3-(2-pyridinyl)-1,2,4-oxadiazole | 5-(2-naphthyl)-3-(2-pyridyl)-1,2,4-oxadiazole | 5-naphthalen-2-yl-3-pyridin-2-yl-1,2,4-oxadiazole | MLS000063880 | SMR000076702 | cid_926663
Type:
Small organic molecule
Emp. Form.:
C17H11N3O
Mol. Mass.:
273.2887
SMILES:
c1ccc(nc1)-c1noc(n1)-c1ccc2ccccc2c1
Structure:
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