Reaction Details Report a problem with these data
Target
Luciferin 4-monooxygenase
Ligand
BDBM50478348
Substrate
n/a
Meas. Tech.
ChEMBL_476211 (CHEMBL923742)
IC50
60±n/a nM
Citation
 Auld, DS; Southall, NT; Jadhav, A; Johnson, RL; Diller, DJ; Simeonov, A; Austin, CP; Inglese, J Characterization of chemical libraries for luciferase inhibitory activity. J Med Chem 51:2372-86 (2008) [PubMed]  Article 
Target
Name:
Luciferin 4-monooxygenase
Synonyms:
LUCI_PHOPY | Luciferase
Type:
PROTEIN
Mol. Mass.:
60747.46
Organism:
Photinus pyralis
Description:
ChEMBL_938513
Residue:
550
Sequence:
MEDAKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSGSTGLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVVPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGELPAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILIKAKKGGKSKL
  
Inhibitor
Name:
BDBM50478348
Synonyms:
CHEMBL406835
Type:
Small organic molecule
Emp. Form.:
C19H12O3
Mol. Mass.:
288.2968
SMILES:
Oc1ccccc1-c1cc(=O)c2c(ccc3ccccc23)o1
Structure:
Search PDB for entries with ligand similarity: