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Target
Reverse transcriptase
Ligand
BDBM50168995
Substrate
n/a
Meas. Tech.
ChEMBL_545151 (CHEMBL1018093)
IC50
>1150000±n/a nM
Citation
 Tan, GT; Pezzuto, JM; Kinghorn, AD; Hughes, SH Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. J Nat Prod 54:143-54[PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50168995
Synonyms:
(-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indolizine-1,2,8-triol | 1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL | CHEMBL371197 | SWAINSONINE
Type:
Small organic molecule
Emp. Form.:
C8H15NO3
Mol. Mass.:
173.2096
SMILES:
O[C@@H]1CN2CCC[C@@H](O)[C@@H]2[C@@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: