Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 8
Ligand
BDBM50420240
Substrate
n/a
Meas. Tech.
ChEMBL_836771 (CHEMBL2075296)
Ki
582000±n/a nM
Citation
 Deguchi, T; Kusuhara, H; Takadate, A; Endou, H; Otagiri, M; Sugiyama, Y Characterization of uremic toxin transport by organic anion transporters in the kidney. Kidney Int 65:162-74 (2004) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 8
Synonyms:
Oat3 | Organic anion transporter 3 | S22A8_RAT | Slc22a8 | rOat3
Type:
PROTEIN
Mol. Mass.:
59199.83
Organism:
Rattus norvegicus
Description:
ChEMBL_1482580
Residue:
536
Sequence:
MTFSEILDRVGSMGPFQYLHVTLLALPVLGIANHNLLQIFTATTPVHHCRPPPNASIGPWVLPLDPNGKPEKCLRFVHLPNASLPNDTQRATEPCLDGWIYNSTRDTIVIEWDLVCSSNKLKEMAQSIFMAGILVGGPVIGELSDRFGRKPILTWSYLMLAASGSGAAFSPSLPVYMIFRFLCGCSISGISLSTVILNVEWVPTSMRAISSTSIGYCYTIGQFILSGLAYAIPQWRWLQLTSSAPFFIFSLLSWWVPESIRWLVLSGKYSKALKTLQRVATFNGKKEEGKKLTIEELKFNLQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFSTGFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITILSLSYLGRRITQSFLLLLAGGAILALIFVPSEMQLLRTALAVFGKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNVWARVGSMIAPLVKITGELQPFIPNVIFGTTALLGGSAAFFLLETLNRPLPETIEDIQNWHKQVQKTKQESEAEKASQIIPLKTGG
  
Inhibitor
Name:
BDBM50420240
Synonyms:
CHEMBL2074590
Type:
Small organic molecule
Emp. Form.:
C10H9NO2
Mol. Mass.:
175.184
SMILES:
CC(=O)Oc1c[nH]c2ccccc12
Structure:
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