Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 2
Ligand
BDBM50420177
Substrate
n/a
Meas. Tech.
ChEMBL_838310 (CHEMBL2076808)
Ki
266000±n/a nM
Citation
 Gorboulev, V; Ulzheimer, JC; Akhoundova, A; Ulzheimer-Teuber, I; Karbach, U; Quester, S; Baumann, C; Lang, F; Busch, AE; Koepsell, H Cloning and characterization of two human polyspecific organic cation transporters. DNA Cell Biol 16:871-81 (1997) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 2
Synonyms:
OCT2 | Organic cation transporter 2 | S22A2_HUMAN | SLC22A2 | hOCT2
Type:
PROTEIN
Mol. Mass.:
62591.01
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1484077
Residue:
555
Sequence:
MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHRCRSPGVAELSLRCGWSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLGPCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKSLPASLQRLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLASVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVHICSSMCDIGGIITPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENMQRPRKNKEKMIYLQVQKLDIPLN
  
Inhibitor
Name:
BDBM50420177
Synonyms:
NICOTINYL METHYLAMIDE
Type:
Small organic molecule
Emp. Form.:
C7H8N2O
Mol. Mass.:
136.1512
SMILES:
CNC(=O)c1cccnc1
Structure:
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