Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 6
Ligand
BDBM50103595
Substrate
n/a
Meas. Tech.
ChEMBL_837481 (CHEMBL2075969)
Ki
>1000000±n/a nM
Citation
 Nagata, Y; Kusuhara, H; Endou, H; Sugiyama, Y Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus. Mol Pharmacol 61:982-8 (2002) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 6
Synonyms:
Oat1 | Organic anion transporter 1 | S22A6_RAT | Slc22a6 | rOAT1 | rROAT1 | renal organic anion transporter 1
Type:
PROTEIN
Mol. Mass.:
60784.17
Organism:
Rattus norvegicus
Description:
ChEMBL_838479
Residue:
551
Sequence:
MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPPHHCRPPANANLSKDGGLEAWLPLDKQGQPESCLRFTSPQWGPPFYNGTEANGTRVTEPCIDGWVYDNSTFPSTIVTEWNLVCSHRAFRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCVFRLLSGMSLASIAINCMTLNVEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLVVSVPFFIAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEEGAKLSIEVLRTSLQKELTLSKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQMASLLLAGICILVNGIIPKSHTIIRTSLAVLGKGCLASSFNCIFLYTGELYPTVIRQTGLGMGSTMARVGSIVSPLVSMTAEFYPSMPLFIFGAVPVVASAVTALLPETLGQPLPDTVQDLKSRSRGKQNQQQQEQQKQMMPLQASTQEKNGL
  
Inhibitor
Name:
BDBM50103595
Synonyms:
Brumetadina | CHEBI:3699 | Cimetidine | Tagamet | Tagamet HB | Tagamet HB 200 | Valmagen
Type:
Small organic molecule
Emp. Form.:
C10H16N6S
Mol. Mass.:
252.339
SMILES:
CN\C(NC#N)=N/CCSCc1nc[nH]c1C
Structure:
Search PDB for entries with ligand similarity: