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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50032425
Substrate
n/a
Meas. Tech.
ChEMBL_202059 (CHEMBL813142)
Ki
283±n/a nM
Citation
 Danso-Danquah, R; Bai, X; Zhang, X; Mascarella, SW; Williams, W; Sine, B; Bowen, WD; Carroll, FI Synthesis and sigma binding properties of 1'- and 3'-halo- and 1',3'-dihalo-N-normetazocine analogues. J Med Chem 38:2986-9 (1995) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50032425
Synonyms:
7-Bromo-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol | CHEMBL103458
Type:
Small organic molecule
Emp. Form.:
C19H26BrNO
Mol. Mass.:
364.32
SMILES:
[#6]-[#6]1-[#6]-2-[#6]-c3ccc(-[#8])c(Br)c3C1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](/[#6])-[#6] |TLB:9:11:1:16.14.15,17:16:1:11.4.3|
Structure:
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