Reaction Details Report a problem with these data
Target
Glutamine synthetase, chloroplastic
Ligand
BDBM50487068
Substrate
n/a
Meas. Tech.
ChEMBL_927331 (CHEMBL3069532)
Ki
55000±n/a nM
Citation
 Occhipinti, A; Berlicki, ?; Giberti, S; Dziedzio?a, G; Kafarski, P; Forlani, G Effectiveness and mode of action of phosphonate inhibitors of plant glutamine synthetase. Pest Manag Sci 66:51-8 (2010) [PubMed]  Article 
Target
Name:
Glutamine synthetase, chloroplastic
Synonyms:
6.3.1.2 | GLN2 | GLNAC_MAIZE | GS2 | Glutamate--ammonia ligase | Glutamine synthetase, chloroplastic
Type:
PROTEIN
Mol. Mass.:
46017.95
Organism:
Zea mays
Description:
ChEMBL_105559
Residue:
423
Sequence:
MAQAVVPAMQCRVGVKAAAGRVWSAGRTRTGRGGASPGFKVMAVSTGSTGVVPRLEQLLNMDTTPYTDKVIAEYIWVGGSGIDIRSKSRTISKPVEDPSELPKWNYDGSSTGQAPGEDSEVILYPQAIFKDPFRGGNNVLVICDTYTPQGEPLPTNKRHRAAQIFSDPKVGEQVPWFGIEQEYTLLQKDVNWPLGWPVGGFPGPQGPYYCAVGADKSFGRDISDAHYKACLYAGINISGTNGEVMPGQWEYQVGPSVGIEAGDHIWISRYILERITEQAGVVLTLDPKPIQGDWNGAGCHTNYSTKTMREDGGFEEIKRAILNLSLRHDLHISAYGEGNERRLTGKHETASIGTFSWGVANRGCSIRVGRDTEAKGKGYLEDRRPASNMDPYIVTGLLAETTILWQPSLEAEALAAKKLALKV
  
Inhibitor
Name:
BDBM50487068
Synonyms:
3,5-DIMETHYLPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID
Type:
Small organic molecule
Emp. Form.:
C9H15NO6P2
Mol. Mass.:
295.166
SMILES:
Cc1cc(C)cc(NC(P(O)(O)=O)P(O)(O)=O)c1
Structure:
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