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Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50038215
Substrate
n/a
Meas. Tech.
ChEMBL_139963 (CHEMBL749018)
Ki
37±n/a nM
Citation
 Moltzen, EK; Pedersen, H; Bøgesø, KP; Meier, E; Frederiksen, K; Sánchez, C; Løve Lembøl, H Bioisosteres of arecoline: 1,2,3,6-tetrahydro-5-pyridyl-substituted and 3-piperidyl-substituted derivatives of tetrazoles and 1,2,3-triazoles. Synthesis and muscarinic activity. J Med Chem 37:4085-99 (1995) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51390.46
Organism:
RAT
Description:
P08482
Residue:
460
Sequence:
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50038215
Synonyms:
5-(2-Butyl-2H-tetrazol-5-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine | CHEMBL334493
Type:
Small organic molecule
Emp. Form.:
C11H19N5
Mol. Mass.:
221.3021
SMILES:
CCCCn1nnc(n1)C1=CCCN(C)C1 |t:10|
Structure:
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